鲍小平简介
【个人简介】
鲍小平，男，理学博士，教授。主要从事生物活性分子合成、性质评价及作用机制研究和阴离子受体化学研究(包括阴离子物种的识别、传感及跨膜运输)。截至2024年，已主持国家和省部级项目共10项(包括国家自然科学基金3项、贵州省自然科学基金重点项目1项、贵州省科技拔尖人才项目1项和教育部科学技术研究重点项目1项)，以第一作者或通讯作者在Chem. Commun.、J. Org. Chem.、Sens. Actuators B、J. Agric. Food Chem.、Pest Manag. Sci.和Chin. Chem. Lett.等期刊共发表学术论文60余篇，授权发明专利3件。
邮箱：baoxp_1980@aliyun.com
【主持项目】
1. 国家自然科学基金地区项目“新型咖啡酸-噻唑杂合物的设计合成、抗植物病原细菌活性及作用机制研究”(No. 32060626)
2. 国家自然科学基金地区项目“新型1,2,4-三唑联喹唑啉类衍生物的设计、合成及抗菌活性研究”(No. 21362003)
3. 国家自然科学基金地区项目“新型环状阴离子受体的合成及识别传感性质研究”(No. 21161005)
4. 贵州省自然科学基金重点项目“含噻唑单元的新型咖啡酸类衍生物的合成及农用活性研究”
(黔科合基础[2020]1Z025)
5. 贵州省科技拔尖人才支持计划项目“新型喹唑啉(酮)-噻唑类缀合物的设计合成及其农用抗菌活性研究”(黔教合KY字[2018]038)
【学术论文】
1. Songsong Liu, Hong Li, Sha Li, Mingman Sun, and Xiaoping Bao* Discovery of New Benzohydrazide Derivatives Containing 4‑Aminoquinazoline as Effective Agricultural Fungicides, the Related Mechanistic Study, and Safety Assessment, J. Agric. Food Chem., 2025, 73,2830−2841.
2. Taisen Yan, Hong Li, Sha Li, Shengping Liu, and Xiaoping Bao* Discovery of Novel Quinazolinone-2-carbohydrazide Derivatives as Effective Succinate Dehydrogenase Inhibitors and Biosafety Assessment on Rice and Zebrafish, J. Agric. Food Chem., 2025, 73,5054−5066.
3. Yehui Yang, Songsong Liu, Taisen Yan, Mingyan Yi, Hong Li, and Xiaoping Bao* Design, Synthesis, Antifungal Activity, and Mechanism of Action of New Piperidine-4-carbohydrazide Derivatives Bearing a Quinazolinyl Moiety,J. Agric. Food Chem.,2024, 72,17283−17294.
4. Nan Wu, Yehui Yang, Guangmin Tian, Lian An, Songsong Liu, Taisen Yan, Mingyan Yi, and Xiaoping Bao* Synthesis, X‑ray Crystal Structure, and Antimicrobial Studies of New Quinazolin-4(3H)‑oneDerivatives Containing the 1,2,4-Triazolo[3,4‑b][1,3,4]thiadiazole Moiety and 4‑Piperidinyl Linker,J. Agric. Food Chem.,2023, 71, 19277−19287.
5. Junhong Li, Lisha Yuan, Qinrong Yang, Ningjin Zhang,* Tao Sun,* and Xiaoping Bao* A Carbazole-1,8-Disulfonamide-Derived Cryptand Receptor for Anion Recognition,J. Org. Chem., 2023, 88,14753−14759.
6. Su-Ran Wan, Ye-Hui Yang, Guang-Min Tian, Lian An, Song-Song Liu, Ming-Yan Yi, Tai-Sen Yan and Xiao-Ping Bao* Design, synthesis, and antimicrobial evaluation of 2-aminothiazole derivatives bearing the 4-aminoquinazoline moiety against plant pathogenic bacteria and fungi,Pest Manag. Sci., 2023, 79, 4535−4546.
7. Muhan Ding, Nan Wu,Qiao Lin, Ya Yan, Yehui Yang, Guangmin Tian, Lian An, and Xiaoping Bao* Discovery of Novel Quinazoline-2-Aminothiazole Hybrids Containing a 4-Piperidinylamide Linker as Potential Fungicides against the Phytopathogenic Fungus Rhizoctonia solani,J. Agric. Food Chem., 2022, 70, 10100−10110.
8. Jun Shi, Na Luo, Muhan Ding, Xiaoping Bao* Synthesis, in vitro antibacterial and antifungal evaluation of novel 1,3,4-oxadiazolethioether derivatives bearing the 6-fluoroquinazolinylpiperidinyl moiety, Chin. Chem. Lett., 2020, 31, 434–438.
9. Xiaoping Bao, Xin Wu, Stuart N. Berry, Ethan N. W. Howe, Young-Tae Chang and Philip A. Gale*, Fluorescent squaramides as anion receptors and transmembrane anion transporters,Chem. Commun., 2018, 54, 1363−1366.
10. Xiaoping Bao*, Yuhui Zhou, Baoan Song*. Recognition and sensing properties of a quinazolinylaminothiourea-based anion receptor in non-aqueous and aqueous CH3CN-DMSO medium. Sens. Actuators B, 2012, 171-172, 550−555.
【授权专利】
1. 鲍小平，闫柏任，吕新阳，杜欢一种含1,2,4-三氮唑硫醚的喹唑啉酮类化合物及其合成方法和应用，ZL 201510277539.6
2. 鲍小平，杨岚，石军，罗娜一种用于制备防治作物致病细菌药物的化合物及制备方法，ZL 201810349696.7
3. 鲍小平, 吴楠, 刘松松, 鄢泰森, 易茗艳含1,2,4-三唑[3,4-b][1,3,4]噻二唑的喹唑啉-4-酮类化合物及制备及用途，ZL 202310633765.8
